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Studies have shown that the frequency of MSCs in cord blood ranges from about 0.001% to 0.01% of the total nucleated cells present in the cord blood sample.
Cryopreserved cord blood stem cells are stored at very low temperatures (typically around -196°C) to preserve their viability for potential future use. While cryopreservation is a widely used and effective method for storing stem cells, there are some potential risks and challenges associated with the process.
The freezing and thawing process can potentially cause damage to the cells, affecting their viability and functionality. While cryoprotectants are used to help protect the cells during freezing and thawing, there is still a risk of some degree of cell damage. Our team of distribution experts is here to provide you with expert guidance and support every step of the way. We'll work with you to develop a customized distribution strategy that meets your business needs and goals.
There is a risk of contamination during the collection, processing, and storage of cord blood stem cells. Contaminants such as bacteria or fungi can compromise the quality of the stored cells and may render them unusable for transplantation.
If there are issues with the storage conditions or equipment, such as temperature fluctuations or equipment failure, it could impact the viability of the stored stem cells.
The long-term viability of cryopreserved stem cells is not fully understood, and there is a possibility that stored cells may lose some of their potency or functionality over time.
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Thawing frozen stem cells requires careful handling and precise protocols to ensure the cells are not further damaged during the process. Improper thawing techniques can affect the quality of the cells.
There is a risk that stem cells could develop into tumors if they are not properly controlled or if they undergo abnormal growth.
There is a risk of infection at the site where the stem cells are collected or administered.
The recipient's immune system may recognize the transplanted stem cells as foreign and reject them.
Stem cells may differentiate into unintended cell types, leading to unwanted outcomes. If there are issues with the storage conditions or equipment, such as temperature fluctuations or equipment failure, it could impact the viability of the stored stem cells.
Age-Related Changes: As individuals age, the proliferative capacity and regenerative potential of adult stem cells may decline. This can affect the ability of stem cells to divide and differentiate into various cell types for tissue repair and regeneration.
DNA Integrity: Over time, adult stem cells can accumulate DNA damage due to factors such as exposure to environmental stressors, oxidative stress, and natural aging processes. This can affect the function and potency of stem cells
Cellular Function: Aging can lead to changes in the microenvironment surrounding stem cells, affecting their functionality and regenerative abilities. This may impact the potency of adult stem cells in older individuals.
There is a risk of contamination during the collection, processing, but painful when drawing from Bone marrow. Typically collected from the pelvic bone or sternum using a needle inserted into the bone marrow cavity.
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